Studies and Trials in Memory Care: the news, the names and what changed.
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Arrowhead Pharmaceuticals, Inc. on Wednesday shared interim data from an ongoing Phase 1/2a clinical trial for ARO-MAPT, an investigational RNA interference therapy targeting Alzheimer's disease and other tau-related disorders. These early findings provide the first clinical validation of a novel platform…
Updated October 14, 2026 | Reviewed by Monica Vilhauer Ph.D. A paper published recently in Frontiers in Systems Neuroscience is making some waves in trauma circles, and for good reason. Written by Steven Kotler, Michael Mannino, Glenn Fox, and Karl Friston, it takes…
Artificial intelligence tools have emerged as a potential means of extending the capabilities of health care workers, including in primary care settings. Large language models (LLMs) known as chatbots have performed well in simulations. However, little is known about how…
The new analyses indicate that there were fewer countable motor seizures as early as two weeks following bexicaserin treatment initiation and that these reductions were maintained over a full year of open label observation. This observed response was consistent across…
Certain common genetic changes might make some people with focal epilepsy less responsive to seizure medications, finds a new global study led by researchers at UCL and UTHealth Houston. Focal epilepsy is a condition where seizures start in one part…
A multi-cohort transcriptomic, genetic, and experimental study identifies the RHBDF2–ADAM17–TNFα axis as a molecular bridge linking ulcerative colitis to blood–brain barrier disruption and dementia risk. Subject of Research: Molecular mechanisms linking ulcerative colitis to blood–brain barrier disruption and…
A new coordinate-based network mapping study suggests that the scattered gray matter abnormalities reported in idiopathic generalized epilepsy converge most consistently on a subcortical functional network centered on the thalamus and putamen. News Source: Kendall Mcintyre. (October 15, 2026). Scattered Gray Matter…
Cells long viewed as guardians of brain health may have a darker side in old age. New research suggests that oligodendrocytes, the cells that build and maintain the insulating coating around nerve fibers, can become dysfunctional and help drive the…
Some people keep memories as sharp as those of young adults, even as they age. In some cases, cognitive function holds up even when dementia-causing proteins build up in the brain. The answer lay in an enzyme that breaks down…
At a recent seminar, I talked about executive function while having patients actually walk. Hearing the term 'executive function' alone might make it feel a bit disconnected from walking. These are terms that come up when studying higher brain dysfunction,…